lateral reticular nucleus
Acronym:
LRN
The term lateral reticular nucleus (LRN) refers to a group of cells defined on the basis of Nissl and cholinergic stains, that is located ventrolaterally in the medullary reticular formation (MRF) of the human ( Carpenter-1983, Paxinos-2012 ) ), the macaque ( Martin-2000 ), the rat ( Swanson-2004 ) and the mouse ( AMBA-2024 ). It is divided into a magnocellular part of the lateral reticular nucleus (LRNmc)and parvicellular part of the lateral reticular nucleus (LRNpc) (not to be confused with the parvicellular reticular nucleus (PCR)). The lateral reticular nucleus as defined by Nissl stain is not subdivided in most textbooks and brain atlases of primates. The A1 cell group of noradrenergic neurons is found in its vicinity ( Dahlstrom-1964; Felten-1983 ). Functionally it belongs to the postcerebellar and precerebellar nuclei of the behavior control column ( Swanson-2004 ).
Paxinos-2012 segments the LRN into three parts based on stains for acetylcholine (ACH) and norepinephrine (NE) in addition to Nissl substance. They include LRNpc, the lateral reticular nucleus, subtrigeminal part of Paxinos (LRNs5), which has, in addition to the cholinergic cells found in all of the LRN, noradrenergic cells of the A1 cell group; and, by far the largest part of the remaining LRNmc, the lateral reticular nucleus, proper part of Paxinos (LRNpr). Brain atlases in which LRN is segmented according to this scheme include those of the human ( Paxinos-2012 ), macaque ( Paxinos2009a ), rat ( Paxinos 2009b ) and mouse ( Franklin-2008 ). Updated 20 Jan 2026 )
Also known as: Nucleus reticularis lateralisNeuroNames ID : 727
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